Here's a nice, basic guide to lettering in Adobe Illustrator. The crystallize tool is something I didn't know about, and the quick arrangement of the sound effect graphic is pretty cool.
A similar method is demonstrated well in this time-lapse video.
And off of those, I found this really nice video of this guy Gerry Alanguilan inking and colouring a large-scale work. There's a longer version with commentary here. The commentary is in a mixture of English and Tagalog (which is pretty cool) with handy subtitles in English. (BTW, he uses UNI drawing pens, points 0.1, 0.2, 0.3, 0.5 and 0.8 to ink his stuff.) I love his style.